An International Peer Reviewed Research Journal

AJP

SSN : 0971 - 3093

Vol  6, No 4, October-December, 1997

Asian Journal of Physics                                                                                                           Vol 6, No 4 (1997) 477-491


Study of the torsion, inversion and tilt angle variation of the
 amino group in some local anesthetics


M ALCOLEA PALAFOX

Departamento de Quìmica-Fìsica I (Espectroscopia) Facultad de Ciencias Quìmicas.

Universidad Complutense, Madrid-28040, SPAIN

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In the p-amino group of the local anesthetics Benzocaine and Procaine of free basis, the pathway of minimum energy was obtained, corresponding to the torsion and inversion motions with a simultaneous change of the tilt angle, using the AM 1 and CNDO/2 semiempirical methods. The optimum geometric parameters and related potential functions were determined. The Raman bands in the 100-600 cm-1 range were recorded and identified.

Study of the torsion, inversion and tilt angle variation of the amino group in some local anesthetics.pdf
M ALCOLEA PALAFOX

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