An International Peer Reviewed Research Journal

AJP Vol 30 No 2, 2021

AJP

SSN : 0971 - 3093

Vol 30, No 2, February, 2021


Asian


Journal of Physics

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Volume 30                                                               No 2                                                              February 2021

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Anita Publications
FF-43, 1st Floor, Mangal Bazar, Laxmi Nagar, Delhi-110 092, India

Asian Journal of Physics                                                                                                       Vol. 30 No 2, 2021, 219-238


Wolfgang Kiefer – Multi-Talented German Physicist

Rajinder Singh
Research Group: Physics Education and History of Science.
Physics Department, Institute of Physics. University of Oldenburg. 26111 Oldenburg, Germany
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I have written more than 30 books and a number of articles on scientists and politicians. However, I have no experience of writing on a living legend, like Prof Wolfgang Kiefer. Professor Vinod Rastogi, Editor-in-Chief, Asian Journal of Physics, told me that he is planning to organize a special issue of AJP honouring him on the occasion of his 80th birthday on Feb 12, 2021, and invited me to contribute something. I happily agreed, as I know Professor Kiefer for a while, though, only through correspondence, and never had the opportunity to meet him personally.

Wolfgang Kiefer – Multi-Talented German Physicist.pdf
Rajinder Singh

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 239-250


An Interview with Wolfgang Kiefer
(On the occasion of 80th birthday of Wolfgang; Feb 12, 2021)

V K Rastogi
Indian Spectroscopy Society, KC-68,1. Old Kavinagar, Ghaziabad-201 002, India
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The effect known as Raman Effect was first demonstrated experimentally on Feb 28, 1928 by Prof Chandrasekhara Venkata Raman at the Indian Association for Cultivation of Sciences, Calcutta (India). After the discovery of Raman Effect in 1928, the researchers all over the world became interested in this new technique which is based on the inelastic scattering of light. In 1929, G Joos, wrote a complete chapter: "The Raman Effect" in German "Encylopaedia of Experimental Physics". In the same year (1929), the importance of the effect in relevance to chemistry was given by C Schäfer and F Matossi in a monograph “Fortschritte der Chemie, Physik und Physikalische Chemie”. In 1931, K W F Kohlrausch published “Der Smekal-Raman-Effekt”, in which he gave 417 references1. For the first time, the term " Raman Effect" was introduced to the scientific literature by one of the Raman's junior colleagues, L A Ramdas through a short note which appeared in the 14th July issue of Nature in 1928. Also for the first time the term "Raman Effect" appeared in Title- Index of Vol 122 of Nature in 1928.

An Interview with Wolfgang Kiefer.pdf
Vinod Rastogi

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 251-257


C V Raman: One of the most brilliant physicists of the 20th century


Anjana Chattopadhyay

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Sir C V Raman was an illuminating genius and a devoted scientist, who made towering contributions in the development of science in India. Brief history of his life and legacy has been described here. He worked on different fields such as musical acoustics, light scattering, crystal dynamics and optics. He will be remembered for his brilliant discovery of Raman Effect for which he received the Noble Prize in Physics in 1930. He explained the mystery of blue colour of sea water, optical phenomenon of diamond, gems, opals etc. He created the School of Physics and the Raman Research Institute, Bangalore. He founded the Indian Academy of Sciences and started the Indian Journal of Physics.

References

  1.   Raman C V (Sir Chandrasekhara Venkata Raman), Encyclopædia Britannica, Inc. 5 March 2020; Retrieved 28 Sept. 2020.

  2.   Venkataraman G, Journey into Light: Life and Science of C V Raman, (Bangalore: Indian Academy of Sciences), 1988, ISBN 818532400X.

  3.   Parameswaran U, C V Raman: A Biography, (New Delhi:Penguin Books India Pvt Ltd), 2011, pp 27-39.

  4.   Raman C V, Unsymmetrical band due to a rectangular aperture, Philos Mag, 12(1906)494-498.

  5.   "Sir Venkata Raman – Biographical". Nobel Prize – Official website. Retrieved 27 October 2020.

  6.   Singh R, C V Raman and the Discovery of the Raman Effect, Physics in Perspective, 4(2002)399-420.

  7.   Jayaraman A, Chandrasekhara Venkata Raman: A Memoir, (Indian Academy of Sciences, Bengaluru),1989.

  8.   Mukherji P, Mukhopadhyay A, Sir Chandrasekhara Venkata Raman (1888–1970), History of the Calcutta School of Physical Sciences, ( Springer Singapore), 

        2018, pp-22-76.

  9.   Singh R. The 90th Anniversary of the Raman Effect, Indian J Hist Sci, 53(2018)50-58.

10.   The Nobel Prize in Physics 1930 Sir Venkata Raman, Official Nobel prize biography, nobelprize.org.

11.   Raman C V, On the mechanical theory of the vibrations of bowed strings and of musical instruments of the violin family, with experimental verification of the 

        results-Part I (PDF). Bulletin of the Indian Association for the Cultivation of Science, 15(1918)1-158.

12.   Raman C V, Experiments with mechanically-played violins, Proceedings of the Indian Association for the Cultivation of Science, 6(1920)19-36.

13.   Raman C V, Sutherland G A, Whispering-Gallery Phenomena at St. Paul's Cathedral, Nature, 108(1921)42; doi.org/10.1038/108042a0.

14.   Raman C V, On whispering galleries (PDF). Bulletin of the Indian Association for the Cultivation of Science. 7(1922)159-172.

15.   Jayaraman A, Ramdas A K, Chandrasekhara Venkata Raman, Physics Today, 41(1988)56-64.

16.   Singh R, Riess F, The Nobel Laureate Sir Chandrasekhara Venkata Raman, FRS and His Contacts with the British Scientific Community in a Social and 

        Political Context. Notes and Records of the Royal Society of London, 58(2004)47-64.

17.   Ramanathan K R, The Transparency and Color of the Sea, Phys Rev, 25(1925)386-390.

18.   Rayleigh J W S, Colours of Sea and Sky, Nature, 83(1910)48-50.

19.   Raman C V, A new radiation, Indian J Phys, 2(1928)387-398. Book Review vii.

20.   Raman C V, The Colour of the Sea, Nature, 108(1921)367; doi.org/10.1038/108367a0.

21.   Krishnan K S, On the molecular scattering of light in liquids, Philos Mag, 50(1925)697-715.

22.   Mallik D C V, The Raman Effect and Krishnan's Diary. Notes and Records of the Royal Society of London, 54 (2000)67-83.

23.   Chari T K Srinivasa. The illustrious scientists who teamed with C V Raman. Madras Musings, Archive, 22 (22). March 1-15 (2013).. 

        http://madrasmusings.com/Vol%2022%20No%2022/the-illustrious-scientist-who-teamed-with- cv-raman.html; Retrieved 5 Oct, 2020.

24.   Raman C V, Krishnan K S, Magnetic double-refraction in liquids. part I.—benzene and its derivatives, Procd Royal Soc, London, Series A, Containing Papers 

        of a Mathematical and Physical Character, 113(1927)511-519.

25.   Raman C V, Krishnan K S, A new type of secondary radiation, Nature, 121(1928)501-502.

26.   Raman C V, A Change of Wave-length in Light Scattering, Nature, 121(1928)619; doi.org/10.1038/121619b0

27.   Master B R, C V Raman and Raman Effect. Optics and Photonics News, March (2009), 41-45.https:// 

        www.osaopn.org/home/articles/volume_20/issue_3/features/c_v_raman_and_the_raman_effect/ Retrieved on 6 November, 2020.

28.   Singh R, C V Raman and the Press, Scientific reporting and image building. Part I-III, (Shaker Publisher, Dueren, Germany, 2019-2020.

29.   Singh R, Riess F, Sir C V Raman and the story of the Nobel prize, Curr Sci, 75(1998)965-971.

30.   C V Raman, (OSA. The Optical Society, Washington, DC, USA);. 12 June 2013. Retrieved 8 March 2020.

31.   Singh R, 80 Years Ago - the Discovery of the Raman Effect at the Indian Association for the Cultivation of Science, Kolkata, India, Indian J Phys

        82(2008)987-1001.

32.   C V Raman: A Pictorial Biography, (Indian Academy of Sciences India), 1988, pp 147-148.

33.   Malhotra I, C V Raman and the Bharat Ratna, (2014), www.freedomfirst.in. Retrieved 14 November 2020.

34.   Singh R, The Story of C V Raman's resignation from the Fellowship of the Royal Society London, Curr Sci, 83 (2002)1157-1158.

35.   Kendall C, Isabelle M, Bazant-Heggemark F, Hutchings J, Orr L, Babrah J, Baker R. Stone N, Vibrational Spectroscopy: a clinical tool for cancer diagnosis, 

        Analyst, 6(2009)1029-1045.

36.   Indian Academy of Sciences, Prof C V Raman: President from 1934 to 1970. https://www.ias.ac.in/About_IASc/History/Prof._C._V._Raman. Retrieved 14 

        November 2020.

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 259-272


The Best is Yet To Be: Raman Effect - Past, Present and Future


V B Kartha*

The Past

                “-----the study of light-scattering might carry one into the deepest problems of physics and chemistry---“. [1]. These prophetic words, spoken by Sir C.V. Raman, in his Nobel lecture on December 11-1930, are never so true as they are today, more than 90 years after the discovery of the “Raman Effect”. Raman said, “The universality of the phenomenon, the convenience of the experimental technique and the simplicity of the spectra obtained enable the effect to be used as an experimental aid to the solution of a wide range of problems in physics and chemistry.” Raman had already visualized why and how this will happen, when he stated “The frequency differences determined from the spectra, the width and character of the lines appearing in them, and the intensity and state of polarization of the scattered radiations enable us to obtain an insight into the ultimate structure of the scattering substance”. How prophetic he was when he stated “It follows that the new field of spectroscopy has practically unrestricted scope in the study of problems relating to the structure of matter.” !

References

  1.   Sir Chandrasekhara V Raman C V, “The molecular scattering of light”, Nobel Lecture, December 11, 1930, In Nobel Lectures, Physics 1922-1941”, (Elsevier 

        Publishing Company, Amsterdam), 1965.

  2.   (a) Dixit, M N, Prasad N S K, Kartha V B, Laser Raman spectra and free and restricted rotation in phenyl silicates, J Chem Sci, 102(1990)635-641.

        (b) D'Cunha Romola, Kartha V B, Gurnani S, Raman and I.R. studies of the antileprotic drug Dapsone, Spectrochim Acta, A39(1983)331-336.

        (c). Kartha V B, The Rise of the Phoenix- from Sunlight to Lasers, Science Today, 53-56, (Nov. 1978).

  2.   (d) Kartha V B, Leitch L C, Mantsch H H, Infrared and Raman spectra of alkali palmityl sulfates, Canad J Chem, 62(1984)128-132.

  3.   Javier J, An Introduction to Raman Spectroscopy: Introduction and Basic Principles, spectroscopynow.com, Wiley Analytical Science, (2014).

  4.   Jones R R, Hooper D C, Zhang L, Wolverson D, Valev V K, Raman Techniques: Fundamentals and Frontiers, Nanoscale Res Lett, 14(2019)231;  

        doi.org/10.1186/s11671-019-3039-2.

  5.   Langer J, Aberasturi D Jimenez de, Aizpurua J, Tay L-L, Thomas K G, Tian Z Q, Duyne R P V, Vo-Dinh T, Wang Y, Willets K A, Xu C, Xu H, Xu Y, 

        Yamamoto Y S, Zhao B, Liz-Marzán L M, Present and Future of Surface-Enhanced Raman Scattering, ACS Nano, 14(2020)28-117.

  6.   Yu Y, Xiao T-H, Wu Y, Li W, Zeng Q G, Long Li, Li Z-Y, Roadmap for single-molecule surface-enhanced Raman spectroscopy, Advanced Photonics

        2(2020); doi.org/10.1117/1.AP.2.1.014002.

  7.   Kneipp K, Kneipp H, Kartha V B, Manoharan R, Deinum G, Itzkan I, Dasari, Feld M S, Detection and identification of a single DNA base molecule using 

        surface-enhanced Raman scattering (SERS), Phys Rev, E 57(1998)R6281; doi.org/10.1103/PhysRevE.57.R6281.,

  8.   Wickramasinghe H K, Chaigneau M, Yasukuni R, Picard G, Ossikovski R, Billion-Fold Increase in Tip-Enhanced Raman Signal, ACS Nano, 8(2014)3421-

        3426.

  9.   Ashkin A, Optical trapping and manipulation of neutral particles using lasers, PNAS, 94(1997)4853-4860.

10.   Lu W, Chen X, Wang L, Li H, Fu Y V, Combination of an Artificial Intelligence Approach and Laser Tweezers Raman Spectroscopy for Microbial 

        Identification, Anal Chem, 92(2020)6288-6296, .

11.   Jijo L, Ganesh M, Mithun N, Shamee S, Santhosh C, Optical Trap Combined with Raman Spectroscopy to Probe Red Blood Cell Behaviour in Certain 

        Intravenous Fluids, J Biomed Photonics Eng, 5(2019); doi: 10.18287/JBPE19.05.040302.

12.   Castaño J A G, Boussekey L, Verwaerde J P, Moreau M, Tobón Y A, Enhancing Double-Beam Laser Tweezers Raman Spectroscopy (LTRS) for the 

        Photochemical Study of Individual Airborne Microdroplets, Molecules, 24(2019)3325; doi.org/10.3390/molecules24183325. .

13.   Nicolson F, Kircher M F, Stone N, Matousek P, Spatially offset Raman spectroscopy for biomedical applications, Chem Soc Rev, 50(2021)556-568.

14.   Mosca S, Dey P, Tabish T A, Palombo F, Stone N, Matousek P, Spatially Offset and Transmission Raman Spectroscopy for Determination of Depth of 

        Inclusion in Turbid Matrix, Anal Chem, 91(2019)994-9000.

15.   Kiefer J, Transmission Raman Spectroscopy for Pharmaceutical Analysis, Am Pharmaceut Rev. (February 12, 2019).

16.   Tuschel D, Exploring Resonance Raman Spectroscopy”, Spectroscopy, 33(2018)12-19.

17.   Wang Z, Li Y, Resonance Raman enhancement optimization in the visible range by selecting different excitation wavelengths, J Biomed Opt, 20(2015) 

        095003; doi.org/10.1117/1.JBO.20.9.095003.

18.   Allen A, Waldron A, Ottaway J M, Carter J C, Angel S M, Hyperspectral Raman Imaging Using a Spatial Heterodyne Raman Spectrometer with a Microlens 

        Array, Appl Spectrosc, 74(2020)921-931.

19.   Gasser C, Gösch M, Ofner J, Lend B, Stand-off Hyperspectral Raman Imaging and Random Decision Forest Classification: A Potent Duo for the Fast, 

        Remote Identification of Explosives, Anal Chem, 91(2019)7712-7718.

20.   Gasser C, González-Cabrera M, Ayora-Cañada M J, Domínguez-Vidal A, Lendl B, Comparing mapping and direct hyperspectral imaging in stand-off Raman 

        spectroscopy for remote material identification, J Raman Spectrosc, 50(2019)1034-1043.

21.   Coman C, Leopold L F, Raman Mapping: Emerging Applications, in “Raman Spectroscopy and Applications,(Ed. Khan M), Intech Open, 2017.

22.   Dhanada V S, George S D, Kartha V B, Chidangil S, Unnikrishnan V K, Hybrid LIBS-Raman-LIF systems for multi-modal spectroscopic applications: a 

        topical review, Appl Spectrosc Rev, (2020); doi.org/10.1080/05704928.2020.1800486.

23.   Wollweber M, Roth B, Raman Sensing and Its Multimodal Combination with Optoacoustics and OCT for Applications in the Life Sciences, Sensors (Basel), 

        19(2019)2387; doi.org/10.3390/s19102387.

24.   Bai X, Oujja M, Sanz M, Lopez M, Dandolo C K, Castillejo M, Detalle Detalle, Integrating LIBS LIF Raman into a single multi-spectroscopic mobile device 

        for in situ cultural heritage analysis, Proc SPIE 11058, Optics for Arts, Architecture, and Archaeology VII, (2019)1105818; doi.org/10.1117/12.2527272.

25.   Shameem K M M, Chawla A, Mallya M, Barik B K, Unnikrishnan V K, Kartha V B; Chidangil S, Laser-induced breakdown spectroscopy-Raman: An 

        effective complementary approach to analyze renal-calculi, J Biophotonics, 11(2018), e201700271; doi.org/10.1002/jbio.201700271.

26.   Blacksberg J, Maruyama Y, Choukroun M, Charbon E, Rossman G R, New Microscopic Laser-Coupled spectroscopy Instrument Combining Raman, LIBS, 

        and Fluoroscence for Planetay Surface Mineralgy, 43rd Lunar and Planetary Science Conference, (2012); The Woodlands, Texas. LPI Contribution No. 1659, 

        id.1510.

27.   Yakovlev V V, Zhang H F, Noojin G D, Denton M L, Thomas R J, Scully M O, Stimulated Raman photoacoustic imaging, PNAS, 107(2010)20335-20339.      28.   Farrell A J, González-Jiménez M, Ramakrishnan G, Wynne K, Low-Frequency (Gigahertz to Terahertz) Depolarized Raman Scattering Off n-Alkanes, Cycloalkanes, and Six-Membered Rings: A Physical Interpretation, J Phys Chem B, 124(2020)7611-7624.

29.   Madzharova F, Heiner Z, Kneipp J, Surface enhanced hyper Raman scattering (SEHRS) and its applications, Chem Soc Rev, 46(2017)3980-3999.

30.   “World health statistics 2020: monitoring health for the SDGs, Sustainable Development Goals”. Geneva: World Health Organization; (2020).

31.   Ten threats to global health in 2019”, https://www.who.int/emergencies/ten-threats-to-global-health-in-2019, (2019).

32.   The India State-Level Disease Burden Initiative, Indian Council of Medical Reasearch, Public Health Foundation of India, Institute for Health Metrics and Evaluation, 2017.

33.   Malini R, Venkatakrishna K, Kurien J, Pai K M, Rao L, Kartha V B, Krishna C M, Discrimination of Normal, Inflammatory, Premalignant and Malignant Oral Tissue: A Raman Spectroscopy Study, Biopolymers, 81(2006)179-193.

34.   Venkatakrishna K, Kurien J, Pai K M, Valiathan M, Kumar N N, Krishna C M, Ullas G, Kartha V B, Optical pathology of oral tissue: a Raman spectroscopy diagnostic method, Curr Sci, 80(2001)665-669.

35.   Hanlon E B, Manoharan R, Koo T-W, Shafer K E, Motz J T, Fitzmaurice M, Kramer J R, Itzkan I, Dasari R R, . Feld M S, Prospects for in vivo Raman spectroscopy, Phys Med Biol, 45(2000)R1-R59.

36.   Lazaro-Pacheco D, Shaaban A M, Rehman S, Rehman I, Raman spectroscopy of breast cancer, App Spectrosc Rev, 55(2020)439-475.

37.   Aljakouch K, Hilal Z, Daho I, Schuler M, Krauß S D, Yosef H K, Dierks J, Mosig A, Gerwert K, El-Mashtoly S F, Fast and Noninvasive Diagnosis of Cervical Cancer by Coherent Anti-Stokes Raman Scattering, Anal Chem, 91(2019)13900-13906.

38.   Paraskevaidi M, Ashton K M, Stringfellow H F, Wood N J, Keating P J, Rowbottom A W, Martin-Hirsch P-L, Martin F L, Raman spectroscopic techniques to detect ovarian cancer biomarkers in blood plasma, Talanta, 189(2018)281-288.

39.   Nidheesh V R, Mohapatra A K, Unnikrishnan V K, Sinha R K, Nayak R, Kartha V B, Chidangil S, Breath Analysis Techniques: Current Status with special emphasis on spectroscopic detection, Appl Spectrosc Rev, (2020.); doi.10.1080/05704928.2020.1848857.

40.   Fales A (Ed), SERS for Point-of-care and Clinical Applications,1st Edn, ISBN: 9780128205488, Imprint: Elsevier,

41.   Popp J, Biophotonics Technologies Applied at Point of Care, Photonics Spectra Conference 2021, Leibniz Institute of Photonic Technology, Jan 19-22, (2021).

42.   Colceriu-Simon I M, Hedesiu M, Toma V, Armencea G, Moldovan A, Știufiuc G, Culic B,Țărmure V, Dinu C, Berindan-Neagoe I, Știufiuc R I, Băciuț M, The Effects of Low-Dose Irradiation on Human Saliva: A Surface-Enhanced Raman Spectroscopy Study, Diagnostics, 9(2019)101; doi.org/10.3390/diagnostics9030101

43.   Cordero E, Latka I, Matthäus C, Schie I W, Popp J, In-vivo Raman spectroscopy:from basics to applications, J Biomed Opt, 23(2018)071210; doi.org/10.1117/1.JBO.23.7.071210.

44.   Kong K, Kendall C, Stone N, Notingher I, Raman spectroscopy for medical diagnostics — From in-vitro biofluid assays to in-vivo cancer detection, Advanced Drug Delivery Reviews, 89(2015)121-134.

45.   Jyothi Lakshmi R, Kartha V B, Murali Krishna C M, Solomon JGR, Ullas G, Uma Devi P, Tissue Raman Spectroscopy for the Study of Radiation Damage: Brain Irradiation of Mice, Radiation Research, 157(2002)175-182.

46.   Jyothi Lakshmi R, Alexander M, Kurien J, Mahato K K, Kartha V B, Osteo-radionecrosis (ORN) of the Mandible: A Laser Raman Spectroscopic Study, Appl Spectrosc, 57(2003)1100-1116.

47.   Vidyasagar M S, Maheedhar K, Vadhiraja B M, Fernandes D J, Kartha V B, Krishna C M, Prediction of Radiotherapy Response in Cervix Cancer by Raman Spectroscopy: a Pilot Study, Biopolymers, 89(2008)530-537.

48.   Chen H, Das A, Bi L, Choi N, Moon J I, Wu Y, Park S, Choo J, Recent advances in surface-enhanced Raman scattering-based microdevices for point-of-care diagnosis of viruses and bacteria, Nanoscale, 12(2020)21560-21570.

49.   Jacobi L, Damle V H, Rajeswaran B, Tischler Y R, Low-Frequency Raman Spectroscopy as a Diagnostic Tool for COVID-19 and other Coronaviruses, Royal Society Open Science: For Review Only, (07-Apr-2020).

50.   Deckert V, Deckert-Gaudig T, Cialla-May D, Popp J, Zell R, Deinhard-Emmer S, Sokolov A V, Yi Z, Scully M O, Laser spectroscopic technique for direct identification of a single virus I: FASTER CARS, PNAS, 117(2020)27820-27824.

51.   Burkhartsmeyer J, Wang Y, Wong K S, Gordon R, Optical Trapping, Sizing, and Probing Acoustic Modes of a Small Virus, Appl Sci, 10(2020)394; doi.org/10.3390/app10010394.

52.   El-Said W A, Cho H-Y, Choi J-W, SERS Application for Analysis of Live Single Cell, Chapter 16, in Nanoplasmonics - Fundamentals and Applications (ed Grégory Barbillon), (Intech Open), 2017.

53.   Pradhan M, Pathak S, Mathur D, Ladiwala U, Optically trapping tumor cells to assess differentiation and prognosis of cancers, Biomed Opt Express, 7(2016)943-948.

54.   Barkur S, Bankapur A, Pradhan M, Chidangil S, Mathur D, Ladiwala U, Probing differentiation in cancer cell lines by single-cell micro-Raman spectroscopy, J Biomed Opt, 20(2015)085001; doi.org/10.1117/1.JBO.20.8.085001. 

55.   Redding B, Schwab M J and Yong-le Pan Y, Raman Spectroscopy of Optically Trapped Single Biological Micro-Particles, Sensors, 15(2015)19021-19046.

56.   Ralbovsky N M, Egorov V, Moskovets E, Dey P, Dey B K, Lednev I K, Deep-ultraviolet Raman spectroscopy for cancer diagnostics: A feasibility study with cell lines and tissues, Cancer Stud Mol Med Open J, 5(2019)1-10; doi.10.17140/CSMMOJ-5-126

57.   Hamasha K M, Raman Spectroscopy for The Microbiological Characterization and Identification of Medically Relevant Bacteria, Dissertation, Graduate School of Wayne State University, Detroit, Michigan, 2011.

58.   Kiefer K, Surface-Enhanced Raman Spectroscopy for Pharmaceutical Analysis, Am Pharmaceceutical Rev, May 5, 2020.

59.   Krishna C M, Kegelaer G, Adt I, Rubin S, Kartha V B, Manfait M, Sockalingum G D, Combined Fourier transform infrared and Raman spectroscopic approach for identification of multidrug resistance phenotype in cancer cell lines, Biopolymers, 82 (2006)462-470.

60.   Krishna C M, Kegelaer G, Adt I, Rubin S, Kartha V B, Manfait M, Sockalingum G D, Characterisation of Uterine Sarcoma Cell Lines Exhibiting MDR Phenotype by Vibrational Spectroscopy, Biochim Biophys Acta, 1726(2005)160-167.

61.   Qiu G, Xu X, Ji L, Ma R, Dang Z, Yang H, “Surface-Enhanced Raman Spectroscopy to study the biological activity of anticancer agent, Cancer Transl Med, 5(2019)37-41.

62.   Kann B, Offerhaus H L, Windbergs M, Otto C, Raman microscopy for cellular investigations – from single cell imaging to drug carrier uptake visualization, Advanced drug delivery Reviews, 89(2015)71-90.

63.   Sockalingum G D, Charonov S, Beljebbar A, Morjani H, Manfait M, Chourpa I, Raman and SERS spectroscopy for probing drug-target interactions: from in-vitro models to intracellular imaging, Internet J Vibr Spec, [www.irdg.org/ijvs] 3, 5, 3 (1999).

64.   Rajani C, Kincaid J R, Petering D H, A systematic approach toward the analysis of drug-DNA interactions using Raman spectroscopy: the binding of metal-free bleomycins A(2) and B(2) to calf thymus DNA, Biopolymers, 52(1999)110-28.

65.   Tanaka K, Kartha V B, Dasari R R, Feld M, Wang C, Tanaka T, Raman Spectral Studies of Polymer Gels”, Proc. ICORS XV,Vol.1, 360, (John Wiley & Sons, Inc. New York), 1996.

66.   Kartha S B, Kartha V B, Dasari R R, Raman Spectral Studies on the Interaction of PDT Drugs with Model Membranes, Proc ICORS XV, Vol 1, 472, (John Wiley & Sons, New York), 1996.

67.   Nissum M, Jensen P W, Nielsen O F, DNA-Drug Interactions Studied by Surface-Enhanced Raman Spectroscopy Using Visible and Near-Infrared Excitation”, In: (Merlin J C, Turrell S, Huvenne J P (eds), Spectroscopy of Biological Molecules, (Springer, Dordrecht), 1995.

68.   Kartha V B, N.d. Patel N D, Venkateswaran S, Laser Raman Spectroscopic Studies on the Interaction of the Drug Dapsone with Model Membranes, J Chem Sci, (Proc Ind Acad Sci), 102(1990)697-703.

69.   Keller M D, Vargis E, Mahadevan-Jansen A, Granja N D M, Wilson R H, Mycek M A, Kelley M C, Development of a spatially offset Raman spectroscopy probe for breast tumor surgical margin evaluation, J Biomed Opt, 16(2011)077006; doi. 10.1117/1.3600708.

70.   Jermyn M, Mok K, Mercier J, Desroches J, Pichette J, Saint-Arnaud K, Bernst L, Bernstein L, Guiot M-C, Petrecca K, Leblond F, Intraoperative brain cancer detection with Raman spectroscopy in humans, Sci Transl Med, 7(2015)274ra19; doi.10.1126/scitranslmed.aaa2384 (2015).

71.   Sudheendran N, Qi J, Young E D, Lazar A J, Lev D C, Pollock R E, Larin K V, Shih W-C, Line-scan Raman microscopy complements optical coherence tomography for tumor boundary detection, Laser Phys Lett, 11 (2014) 105602 (6pp). .

72.   Barroso E M L, Development of Raman Spectroscopy Tools for Surgery Guidance in Head & Neck Oncology, Thesis, Erasmus University Rotterdam, 2018; ISBN: 978-94-6299-946-6.

73.   Shameem K M M, Dhanada V S, Harikrishnan S, Kartha V B, Chidangil S, Unnikrishnana V K, Echelle LIBS-Raman system: A versatile tool for mineralogical and archaeological applications, Talanta, 208(2020)120482; doi.org/10.1016/j.talanta.2019.120482.

74.   Roman K, Vincent L, Piotr M, Jonathan L, Martin M,Ian S, Greg S, Ed C, Michaela S, Alan S, LiRS combined LIBS, Raman and Fluorescence Astrobiology Payload for potential Europa Lander, EPSC Abstracts, Vol 13, EPSC-DPS2019-1946-1, [Joint Meeting European Planetary Science Congress (EPSC) of the Europlanet Society and the Division for Planetary Sciences (DPS) of the American Astronomical Society (AAS)]. (2019).

75.   Shameem K M M, Dhanada V S, Unnikrishnan V K, A hyphenated echelle LIBS-Raman system for multi-purpose applications, Rev Sci Instruments, 89(2018); doi.org/10.1063/1.5024966.

76.   Das N K, Dai Y, Liu P, Hu C, Tong L, Chen X, Smith Z J, Review Raman Plus X: Biomedical Applications of Multimodal Raman Spectroscopy, Sensors, 17(2017)1592; doi.org/10.3390/s17071592.

77.   Bergholt M S, Zheng W, Lin K, Ho K Y, Teh M, Yeoh K G, So J B Y, Huang Z, Combining near-infrared-excited autofluorescence and Raman spectroscopy improves in vivo diagnosis of gastric cancer, Biosens Bioelectron, 26 (1011)4104-4110.

78.   Ferraro P M, Gambaro G, Curhan G C, Taylor E N, Intake of Trace Metals and the Risk of Incident Kidney Stones, J Urol, 199(2018)1534-1539.

79.   Gleason K M, Heavy Metals, Chronic Malnutrition and Neurodevelopment Among Children in Rural Bangladesh, Doctoral dissertation, Harvard T H, Chan School of Public Health. 2017

80.   Bharatraj D K, Yathapu S R, Nutrition-pollution interaction: An emerging research area, Ind J Med Res, 148(2018)697-704.

81.   Wright R O, Baccarelli A, Metals and Neurotoxicology, J Nutr, 137(2007)2809-2813.

82.   Shameem K M M, Choudhari K S, Bankapur A, Kulkarni S D, Unnikrishnan V K, George S D, Kartha V B, Chidangil S, A hybrid LIBS–Raman system combined with chemometrics: an efficient tool for plastic identification and sorting, Anal Bioanal Chem, 409(2017)3299-3308.

83.   Yao R, Ochoa M, Yan P, Intes X, “Net-FLICS: fast quantitative wide-field fluorescence lifetime imaging with compressed sensing – a deep learning approach, Light Sci Appl, 8(2019)26; doi.org/10.1038/s41377-019-0138-x.

84.   Nair V, Designing synthetic overhead imagery to match a target geographic region: Preliminary results training deep learning models, pg. 948 IGARSS 2020, 2020 IEEE International Geoscience and Remote Sensing Symposium-, (September 26 - October 2, 2020). Virtual Symposium.

85.   Lam C T, Mueller J, Asma B, Asiedu M, Krieger M S, Chitalia R, Dahl D, Taylor P, Schmitt J W, Ramanujam N, An integrated strategy for improving contrast, durability, and portability of a Pocket Colposcope for cervical cancer screening and diagnosis, PLoS One, 13(2018) e0192530; doi.org/10.1371.

86.   Bec J, Phipps J E, Gorpas D, Ma D, Fatakdawala H, Margulies K B, Southard J A, Marcu L, In-vivo label-free structural and biochemical imaging of coronary arteries using an integrated ultrasound and multispectral fluorescence lifetime catheter system, Sci Rep, 7(2017)8960; doi.org/10.1038/s41598-017-08056-0.

87.   The Conversation, Lasers could speed up coronavirus diagnostics, May 7, 2020 10.23 pm AEST

88.   A rapid and label-free platform for virus capture and identification from clinical samples, Yeha Y-T, Gulinob K, Zhang Y H, Sabestien A, Chou T W, Zhou B, Lina Z, Albert I, Lud H, Swaminathana V, Ghedin E, Mauricio Terrones M, PNAS, 117(2020)895-901.

89.   Yacamán M J, Scientists Apply Raman Spectroscopy to COVID-19 Testing, BioPhotonics, Jul/Aug 2020.               

90.   Rao S, John R, Patil A, Unnikrishnan V K, George S D, Pai K M, Ongole R, Devasia T, Kartha V B, Chidangil S, Optical Biopsy and Optical Pathology: Affordable Health Care Under Low-Resource Settings, J biomed Photonics Eng, 6(2020); doi:10.18287/JBPE20.06.020309.

91.   The Renishaw Virsa Raman Analyser; fibre-optic-coupled Raman spectroscopy system with probes for remote analysis, David Reece, Renishaw plc., New 

         Mills, Wotton-under-Edge, Gloucestershire GL12 8JR UK.. September 2019.

92.   ‘Raman Spectroscopy will be useful’, Special Correspondent, The Hindu, Thiruvananthapuram, (Feb.22, 2020).

93.   Overton G, U.S. Navy awarded three spectrophotometry patents for threat detection- Air Biosensors for Detection of Biohazards, Naval Surface Warfare 

        Center, Corona; https://www.navsea.navy.mil/Media/News/ (Sep 23rd, 2019).

94.   (a) Misra A K, Acosta-Maeda T E, Porter J, Sandford M, Sharma S K, Egan M, Abedin M N, Long Range Remote Raman and LIBS Spectroscopy Using a 

         Compact System with Low Laser Pulse Energy, 50th Lunar and Planetary Science Conference, (LPI Contrib. No. 2132) 1674.pdf (2019).

         (b) Misra A K, Acosta-Maeda T E, Porter J N, Egan M J, Sandford M W, Oyama T, Zhou J, Remote Raman Detection of Chemicals from 1752m During 

          Afternoon Daylight, Appl Spectrosc, 74(2020)233-240.

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 273-280

 

Raman Spectroscopy: Twenty-five years of concept to clinical application
for early diagnosis of pre-cancer in Barrett’s Oesophagus


M S Noor Mohamed1, A Dudgeon1,3, E Upchurch2, O J Old1, A Pavlou (deceased)1, L M Almond3,
G R Lloyd1, 6, M Isabelle1, 7, J Hutchings1, C Kendall1, J Day4, N Stone5 and H Barr1.

1Biophotonics Research Unit, Gloucestershire Royal Hospital, Great Western Road, Gloucester GL13NN United Kingdom

2Bristol Royal Infirmary, Bristol, United Kingdom.

3Queen Elizabeth Hospital, Birmingham, United Kingdom

4Bristol Interface Group/Clifton Photonics, University of Bristol , United Kingdom

5Department of Physics and Astronomy, University of Exeter, Exeter, United Kingdom

6MRC Phenome Centre, Birmingham United Kingdom.

7Bioimaging Group, GSK, Shortstown, England United Kingdom

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

Early diagnosis and treatment of all diseases and in particular cancer is important to allow curative treatment. Symptomatic cancer is usually a lethal disease that requires extensive treatment that is enormously challenging for the patient. Over some twenty-five years we have explored the use of Raman to detect molecular changes in precancerous change and cancer of the oesophagus. The aims have been to reduce the subjectivity of histological diagnosis in particular of dysplastic pre invasive cancerous changes in columnar lined (Barrett’s Oesophagus). These changes are often macroscopically invisible and very easily undetectable. Following this we have investigated the development of rapid diagnostic techniques to detect early degeneration in real time without the delays inherent in biopsy and histological analysis. In particular, we have concentrated on the early detection of the macroscopically invisible changes that precede the degeneration to cancer in some patients with Barrett’s Oesophagus. Once these changes are detected the area can we treated using endoscopic techniques and the progression to cancer interrupted without major and life threatening interventions. © Anita Publications. All rights reserved.

Keywords: Vibrational spectroscopy, Raman process, Photoions, Multidimensional spectroscopy

References

  1.   Fitzgerald R C, Di Pietro M, Ragunath K, Ang Y, Kang J Y, Watson P, British Society of Gastroenterology guidelines on the diagnosis and management of 

        Barrett’s oesophagus, Gut, 63(2014)7-42.

  2.   Jankowski J, Molecular Evolution of the Metaplasia-Dysplasia- Adenocarcinoma Sequence in the Esophagus, Am J Pathol, 154(1999)965-973.

  3.   Vieth M, Ell C, Gossner L, Histological analysis of endoscopic resection specimens from 326 patients with Barrett’s esophagus and early neoplasia, 

        Endoscopy, 36(2004)776-781.

  4.   Singh R, Ragunath K, Jankowski J, Barrett’s esophagus: diagnosis, screening, surveillance and controversies, Gut Liver, 1(2007)93-100.

  5.   Kendall C, Hutchings J, Barr H, Shepherd N, Stone N Exploiting the diagnostic potential of biomolecular fingerprinting with vibrational spectroscopy, 

        Faraday Discuss, 149(2011)279-296.

  6.   Isabelle M, Dorney J, Lewis A, Lloyd G R, Old O, Shepherd N, Rodriguez-Justo M, Barr H, Lau K, Bell I, Ohrel S, Thomas G, Stone N, Kendall C, Multi-

        centre Raman spectral mapping of oesophageal cancer tissue: a study to assess system transferability, Faraday Discuss, 187(2016)87-104.

  7.   Old O J, Fullwood L M, Scott R, Lloyd G R, Almond L M, Shepherd N, Stone N, Barrand H, Kendall C, Vibrational Spectroscopy for Cancer Diagnostics, 

        Analytical Methods, 6(2014)3901-3917.

  8.   Almond L M, Hutchings J, Lloyd G, Wadley M, Shepherd N, Sanders S, Day J, Stevens O, Stone N, Kendall C, Barr H, Endoscopic Raman spectroscopy 

        enables objective diagnosis of dysplasia in Barrett’s Oesophagus, GIE, 79(2013)37-45.

  9.   Lloyd G, Almond L M, Stone N, Shepherd N, Sanders S, Hutchings J, Barr H, Kendall C, Utilising non-consensus pathology measurements to improve the 

        diagnosis of oesophageal cancer using a Raman spectroscopic probe. Analyst, 139(2014)381-386.

10.   Upchurch E, Old O J, Lloyd G R, Isabelle M, Kendall C, Shetty G, Pavlou A, Shepherd N, Barr H, Detection of dysplasia in Barrett’s Oesophagus: Are there 

         impending optical and spectroscopic solutions, Gastroenterology, Hepatology and Endoscopy, 3(2016)61-67.

11.   (a) Reid B J, Levine D S, Longton G, Blount P L, Rabinovitch P S, Predictors of progression to cancer in Barrett’s Esophagus: Baseline histology and flow 

         cytometry identify Low- and High-Risk patient subsets, Am J Gastroenterology, 95(200)1669-1676.

        (b) Kallaway C, Almond L M, Barr H, Wood J, Hutchings J, Kendall C, Stone N, Advances in the clinical application of Raman spectroscopy for cancer 

         diagnostics, Photodiagnosis and Photodynamic therapy, 10(2013)207-219.

12.   Moss A, Bourke M J, Hourigan L F, Gupta S, Williams S J, Tran K, Swain M P, Cooper A D, V Kwan V, Bailey A A, Endoscopic resection for Barrett’s High-

        Grade Dysplasia and early esophageal Adenocarcinoma: An essential staging procedure with long-term therapeutic benefit, Am J Gastrolenterol

        105(2010)1276-1283.

13.   Kallaway C, Almond L M, Barr H, Wood J, Hutchings J, Kendall C, Stone N, Advances in the clinical application of Raman spectroscopy for cancer 

        diagnostics, Photodiagnosis and Photodynamic therapy, 10(2013)207-219.

14.   Wang Q S, Wang T, Zhang K H, Biomedical optical spectroscopy for the early diagnosis of gastrointestinal neoplasms, Tumour Biology, 39(2017)1-12.

15.   Keifer W, Recent techniques in Raman Spectroscopy, Advances in infrared and Raman spectroscopy, 3(1977)1-42.

16.   Eliot T S, The Four Quartets: ‘Little Gidding’, Faber and Faber, (UK),1948.

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 281-301


Immuno-SERS microscopy: From SERS nanotag design and correlative single-particle 

spectroscopy to protein localization on single cells and tissue


Michelle Hechler, Supriya Srivastav and Sebastian Schlücker*
Department of Chemistry and Center for Nanointegration Duisburg-Essen (CENIDE),
University Duisburg-Essen, Universitätsstr. 5, 45141 Essen, Germany

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

This review summarizes work from the authors’ laboratory on immuno-surface-enhanced Raman scattering (iSERS) microscopy since the demonstration of its proof of concept in 2006. iSERS microscopy is an emerging bioimaging technique for the selective localization of proteins on single cells and tissue. Selectivity for target proteins is achieved by labeling the corresponding antibodies with SERS labels/nanotags, i.e., molecularly functionalized noble metal nanoparticles for spectral identification. Central advantages of iSERS are multiplexing, quantification, minimization of autofluorescence, no/minimal photobleaching and the need for only a single laser excitation wavelength. The performance of SERS labels/nanotags can be studied in correlative single-particle SERS microspectroscopic and electron microscopic experiments. The rational design of optimal SERS labels/nanotags can be supported by computer simulations predicting the optical properties including the SERS signal enhancement. Work on iSERS from the authors’ group over the past 15 years on the selective localization of target proteins, especially in cancer diagnostics, on tissue and single cells is highlighted. © Anita Publications. All rights reserved.

Keywords: iSERS microscopy, SERS labels/nanotags, (iSECARS), Bioimaging technique.

Total Refs : 60

Immuno-SERS microscopy: From SERS nanotag design and correlative single- particle spectroscopy to protein localization on single cells and tissue.pdf
Michelle Hechler, Supriya Srivastav and Sebastian Schlücker

___________________________________________________________________________________________________________________________________

Asian Journal of Physics                                                                                                       Vol. 30 No 2, 2021, 303-318


Vibrational dynamics via multidimensional electronic spectroscopy


Tobias Brixner

Institut für Physikalische und Theoretische Chemie, Universität Würzburg,

Am Hubland, 97074 Würzburg, Germany

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

Vibrational spectroscopy is commonly performed using infrared radiation for direct transitions between vibrational states or using visible radiation in a Raman process. As an alternative to narrowband lasers, broadband femtosecond pulses can be employed to excite vibrational wave packets whose temporal oscillations contain analogous information. In this review article, it is shown that coherent multidimensional electronic spectroscopy provides a generalization of this idea, such that vibrational information can be retrieved together with ultrafast dynamics and correlations between various electronically excited states. In particular, fluorescence-detected coherent two- and three-dimensional electronic spectroscopy is discussed. This can be realized in a single-beam geometry with shot-to-shot pulse shaping that allows for fast data acquisition and simultaneous measurement of 15 (or more) different four- and six-wave-mixing spectra. These provide information on higher electronically excited states, vibrational dynamics, and exciton transport, for example in supramolecular systems. Generalizations of this idea offer additional spatial resolution on a µm length scale in an optical microscope or even down to the few nm length scale using photoemission electron microscopy. Furthermore, the concept of signal detection was transferred to molecular beams and photoions. A topic of current interest is retrieving the full nonlinear tensor via polarization-shaped laser pulses. In general, multidimensional spectroscopy is a powerful strategy to systematically map out the response of a quantum system for increasing orders of nonlinearity in light–matter interaction. © Anita Publications. All rights reserved.

Keywords: Vibrational spectroscopy, Raman process, Photoions, Multidimensional spectroscopy  

Total Refs: 119

Vibrational dynamics via multidimensional electronic spectroscopy.pdf
Tobias Brixner

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 321-335

 

Determination of accurate absolute Raman cross-sections of

benzene and cyclohexane in the gas phase


Ankit Raj1, Henryk A Witek1,2, and Hiro-o Hamaguchi1,2

1Department of Applied Chemistry and Institute of Molecular Science, National Chiao Tung University, Hsinchu 30010, Taiwan

2Center for Emergent Functional Matter Science, National Chiao Tung University, Hsinchu 30010, Taiwan

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

Absolute Raman cross-section of a Raman transition governs the strength of its observed intensity. The knowledge of this property is crucial in understanding the nature of the Raman tensor and for direct quantitative applications of the Raman intensities. In this study, we determine the absolute differential Raman cross-sections of benzene and cyclohexane: two molecules of fundamental importance, used routinely in studies pertinent to Raman cross-sections. In our experiments, over 15 sets of pressure dependent Raman spectra were acquired on an intensity calibrated Raman spectrometer. The contribution of air, as an impurity, in the pressure readings was quantified. We used pure rotational Raman bands of molecular hydrogen, with known accurate Raman cross-sections as the intensity standards. The Raman cross-sections of the ring breathing mode in benzene (ν2, 992.3 cm–1) and cyclohexane (ν5, 801.3 cm–1) were determined in the gas phase, with uncertainty of 2.7 and 3.5%, respectively. © Anita Publications. All rights reserved.

Keywords: Absolute Raman cross-section, Differential Raman cross-section, Raman intensities, Polarizability, Raman spectroscopy.

References

  1.   Long D A The Raman Effect : A Unified Treatment of the Theory of Raman Scattering by Molecules, (New York: Wiley), 2003.

  2.   Fernández-Sánchez J M, Montero S, Gas-Phase Raman-Scattering Cross-Sections of Benzene and Perdeuterated Benzene, J Chem Phys, 90(1989)2909-2914.

  3.   Avila G, Tejeda G, Fernandez J M, Montero S, The rotational Raman spectra and cross sections of H2O, D2O, and HDO, J Mol Spectrosc, 220(2003)259-275.

  4.   Pelletier M J, Quantitative Analysis Using Raman Spectrometry, Appl Spectrosc. 57(2003)20A-42A.

  5.   McCreery R L Raman spectroscopy for chemical analysis, (New York: J Wiley), 2000.

  6.   Fenner W R, Hyatt H A, Kellam J M, Porto S P S, Raman cross section of some simple gases, J Opt Soc Am, 63(1973)73-77.

  7.   Penney C M, St Peters R L, Lapp M, Absolute rotational Raman cross sections for N2, O2, and CO2, J Opt Soc Am, 64(1974)712-716.

  8.   Röhr H, Rotational raman-scattering of hydrogen and deuterium for calibrating thomson scattering devices, Phys Lett A. 81(1981)451-453.

  9.   Fouche D G, Chang R K, Relative Raman Cross Section for O3, CH4, C3H8, NO, N2O, and H2, Appl Phys Lett, 20(1972)256-257.

10.   Fouche D G, Chang R K, Relative Raman Cross Section for N2, O2, CO, CO2, SO2, and H2S, Appl Phys Lett, 18(1971)579-580.

11.   Colles M J, Griffiths J E, Relative and Absolute Raman Scattering Cross Sections in Liquids, J Chem Phys, 56(1972)3384-3391.

12.   Acosta-Maeda T E, Misra A K, Porter J N, Bates D E, Sharma S K, Remote Raman Efficiencies and Cross-Sections of Organic and Inorganic Chemicals, Appl 

        Spectrosc, 71(2017)1025-1038.

13.   Silva W R, Keller E L, Frontiera R R, Determination of Resonance Raman Cross-Sections for Use in Biological SERS Sensing with Femtosecond Stimulated 

        Raman Spectroscopy, Anal Chem, 86(2014)7782-7787.

14.   McAnally M O, Phelan B T, Young R M, Wasielewski M R, Schatz G C, Van Duyne R P, Quantitative Determination of the Differential Raman Scattering 

        Cross Sections of Glucose by Femtosecond Stimulated Raman Scattering, Anal Chem, 89(2017)6931-6935.

15.   Burns K H, Srivastava P, Elles C G, Absolute Cross Sections of Liquids from Broadband Stimulated Raman Scattering with Femtosecond and Picosecond 

        Pulses, Anal Chem, 92(2020)10686-10692.

16.   Kato Y, Takuma H, Absolute Measurement of Raman-Scattering Cross Sections of Liquids, J Opt Soc Am, 61(1971)347-350.

17.   Skinner J G, Nilsen W G, Absolute Raman Scattering Cross-Section Measurement of the 992 cm−1 Line of Benzene*, Anal Chem, 58(1968)113-119.

18.   Schomacker K T, Delaney J K, Champion P M, Measurements of the Absolute Raman Cross-Sections of Benzene, J Chem Phys, 85(1986)4240-4247.

19.   Udagawa Y, Mikami N, Kaya K, Ito M, Absolute intensity ratios of Raman lines of benzene and ethylene derivatives with 5145 Å and 3371 Å excitation,

        Raman Spectrosc, 1(1973)341-346.

20.   Abe N, Wakayama M, Ito M, Absolute Raman intensities of liquids, J Raman Spectrosc, 6(1977)38-41.

21.   Trulson M O, Mathies R A, Raman Cross-Section Measurements in the Visible and Ultraviolet Using an Integrating Cavity - Application to Benzene, 

       Cyclohexane, and Cacodylate, J Chem Phys, 84(1986)2068-2074.

22.  Raj A, Hamaguchi H, Witek H A, Polarizability tensor invariants of H2, HD, and D2, J Chem Phys. 148(2018)104308; doi.org/10.1063/1.5011433

23.  Raj A, Kato C, Witek H A, Hamaguchi H, Toward standardization of Raman spectroscopy: Accurate wavenumber and intensity calibration using rotational 

       Raman spectra of H2, HD, D2, and vibration–rotation spectrum of O2, J Raman Spectrosc. 51(2020)2066-2082.

24.  Raj A, Witek H A, Hamaguchi H, Vibration–rotation interactions in H2, HD and D2 : centrifugal distortion factors and the derivatives of polarisability 

       invariants, Mol Phys. 118(2020)e1632950; doi.org/10.1080/00268976.2019.1632950.

25.  Komasa J, Piszczatowski K, Łach G, Przybytek M, Jeziorski B, Pachucki K, Quantum Electrodynamics Effects in Rovibrational Spectra of Molecular 

       Hydrogen, J Chem Theory Comput, 7(2011)3105-3115.

26.  Pachucki K, Komasa J, Rovibrational levels of H D, Phys Chem Chem Phys, 12(2010)9188-9196.

27.  Edwards H G M, Long D A, Najm K A B, Thomsen M, The vibration-rotation Raman spectra of 18O2, 17O18O, 17O2 and 16O2, J Raman Spectrosc

       10(1981)60-63.

28.  Okajima H, Hamaguchi H, Accurate intensity calibration for low wavenumber (–150 to 150 cm_–1) Raman spectroscopy using the pure rotational spectrum of 

       N-2, J Raman Spectrosc, 46(2015)1140-1144.

29.   Kirkman I W, Buksh P A, Data acquisition and control using National Instruments’ ‘‘LabVIEW’’ software, Rev Sci Instrum, 63(1992)869-872.

30.   Kalkman C J, LabVIEW: A software system for data acquisition, data analysis, and instrument control, J Clin Monit Comput, 11(1995)51-58.

31.   Onken U, Rarey-Nies J, Gmehling J, The Dortmund Data Bank: A computerized system for retrieval, correlation, and prediction of thermodynamic properties 

        of mixtures, Int J Thermophys, 10(1989)739-747.

32.   Warneck P, Wurzinger C, Chapter 10, Physical and Chemical Properties of the Air, (ed) Fischer G, (Berlin/Heidelberg: Springer-Verlag), 1988.

33.   Nestor J R, Lippincott E R, The effect of the internal field on Raman scattering cross sections, J Raman Spectrosc, 1(1973)305-318.

34.   Eckhardt G, Wagner W G, On the calculation of absolute Raman scattering cross sections from Raman scattering coefficients, J Mol Spectrosc, 19(1966)407-

        411.

35.   Acosta-Maeda T E, Misra A K, Muzangwa L G, Berlanga G, Muchow D, Porter J, Sharma S K, Remote Raman measurements of minerals, organics, and 

        inorganics at 430  m range, Appl Opt, 55(2016)10283-10289.

36.  Carlson R W, Fenner W R, Absolute Raman Scattering Cross-Section of Molecular Hydrogen, Astrophys J 178(1972)551-556.

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 337-345


Effects of charge and alkyl chain configuration on hydrophobic hydration: A temperature-dependent Raman study


Subhadip Roy and Jahur Alam Mondal*

Radiation & Photochemistry Division, Bhabha Atomic Research Centre, Homi Bhabha National Institute, Trombay, Mumbai-400 085, India

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

Hydrophobic hydration is central to macromolecular organization pertaining to chemistry, biology, and applied fields. A delicate balance of hydrophobe-water and water-water interactions dictates the water structure around the hydrophobe. Depending on the size of the hydrophobe, water adopts either tetrahedral or broken hydrogen-bonded structures at the hydrophobic surface. Here, we have investigated the structure of water in the vicinity of molecular hydrophobes that differ from each other either by net charge or by alkyl chain configuration. We have applied Raman difference spectroscopy combined with simultaneous curve fitting analysis (RD-SCF) at variable temperature, which provided the water spectrum (OH stretch) pertaining the hydration shell of the solute at different solution temperatures. Our results show that one-unit positive charge on the hydrophobic group (e.g., tert-butyl alcohol vs. trimethylamine N-oxide) does not affect the tetrahedral structure of water in the hydrophobic hydration shell. On the other hand, the change in alkyl chain configuration from tert-butyl to n-butyl group destabilizes the tetrahedral water structure. © Anita Publications. All rights reserved.

Keywords: Raman spectroscopy, hydrophobic hydration, tetrahedral structure, dangling OH

References

  1.   Meyer E E, Rosenberg K J, Israelachvili J, Recent progress in understanding hydrophobic interactions, Proc Natl Acad Sci (U S A), 103(2006)15739-15746.

  2.   Dyson H J, Wright P E, Scheraga H A, The role of hydrophobic interactions in initiation and propagation of protein folding, Proc Natl Acad Sci (U S A), 

        103(2006)13057-13061.

  3.   Lum K, Chandler D, Weeks J D, Hydrophobicity at small and large length scales, J Phys Chem B, 103(1999)4570-4577.

  4.   Davis J G, Gierszal K P, Wang P, Ben-Amotz D, Water structural transformation at molecular hydrophobic interfaces, Nature, 491(2012)582-585.

  5.   Davis J G, Zukowski S R, Rankin B M, Ben-Amotz D, Influence of a neighboring charged group on hydrophobic hydration shell structure, J Phys Chem B

        119(2015)9417-9422.

  6.   Roy S, Biswas B, Ghosh N, Singh P C, Mondal J A, Hydrophobic hydration of fluoroalkyl (C-F) ss Distinctly different from that of its hydrogenated 

        counterpart (C-H) as observed by Raman difference with simultaneous curve fitting Analysis. J Phys Chem B, 123(2019)27012-27019.

  7.   Robalo J R, Streacker L M, Mendes de Oliveira D, Imhof P, Ben-Amotz D, Vila Verde A, Hydrophobic but water-friendly: favorable water–perfluoromethyl 

        interactions promote hydration shell defects, J Am Chem Soc, 141(2019) 15856-15868.

  8.   Roy S, Biswas B, Ghosh N, Singh P C, Mondal J A, Hydrophobic hydration of fluoroalkyl (C–F) is distinctly different from that of its hydrogenated 

        counterpart (C–H), as observed by Raman difference with simultaneous curve fitting analysis, J Phys Chem C, 123(2019)27012-27019.

  9.   Patra A, Roy S, Saha S, Palit D K, Mondal J A, Observation of extremely weakly interacting OH (~3600 cm–1) in the vicinity of high charge density metal 

        ions (Mz+; Z = 1, 2, 3): A Structural Heterogeneity in the Extended Hydration Shell. J Phys Chem C, 124(2020)3028-3036.

10.   Perera P N, Browder B, Ben-Amotz D, Perturbations of water by alkali halide ions measured using multivariate Raman curve resolution. J Phys Chem B

        113(2009)1805-1809.

11.   Ben-Amotz D, Rankin B M, Hands M D, Wilcox D S, Fega K R, Slipchenko L, Interactions between halide anions and a molecular hydrophobic interface, 

        Faraday Discuss, 160(2013)255-270.

12.   Ahmed M, Namboodiri V, Singh A K, Mondal J A, Sarkar S K, How ions affect the structure of water: A combined Raman spectroscopy and multivariate 

        curve resolution study. J Phys Chem B, 117(2013)16479-16485.

13.   Ahmed M, Singh A K, Mondal J A, Hydrogen-bonding and vibrational coupling of water in a hydrophobic hydration shell as observed by Raman-MCR and 

        isotopic dilution spectroscopy, Phys Chem Chem Phys, 18(2016)2767-2775.

14.   Fega K R, Wilcox D S, Ben-Amotz D, Application of Raman multivariate curve resolution to solvation-shell Spectroscopy, Appl Spectrosc, 66(2012)282-288.

15.   Rankin B M, Hands M D, Wilcox D S, Fega K R, Slipchenko L V, Ben-Amotz D, Interactions between halide anions and a molecular hydrophobic interface, 

        Faraday Discuss, 160(2013)255-270.

16.   Perera P N, Fega K R, Lawrence C, Sundstrom E J, Tomlinson-Phillips J, Ben-Amotz D, Observation of water dangling of bonds around dissolved nonpolar 

        groups. Proc Natl Acad Sci (USA), 106(2009)12230-12234.

17.   Du Q, Superfine R, Freysz E, Shen Y R, Vibrational spectroscopy of water at the vapor/water interface, Phys Rev Lett, 70(1993)2313-2316.

18.   Hare D E, Sorensen C M, Interoscillator coupling effects on the OH stretching band of liquid water, J Chem Phys, 96 (1992)13-22.

19.   Bredt A J, Ben-Amotz D, Influence of crowding on hydrophobic hydration-shell structure, Phys Chem Chem Phys, 22(2020)11724-11730.

20.   Petersen C, Tielrooij K J, Bakker H J, Strong temperature tependence of tater teorientation in tydrophobic tydration Shells, J Chem Phys, 130(2009)214511; 

        doi.org/10.1063/1.3142861.

21.   Ahmed M, Namboodiri V, Mathi P, Singh A K, Mondal J A, How osmolyte and denaturant affect water at the air-water interface and in bulk: A heterodyne-

        detected vibrational sum frequency generation (HD-VSFG) and hydration shell spectroscopic study, J Phys Chem C, 120(2016)10252-10260.

22.   Ahmed M, Singh A K, Mondal J A, Do quaternary methyls (–N+(CH3)3) behave differently from alkyl methyls(R-CH3) in aqueous aedia? J Ind Chem Soc

        95(2018)141-148.

23.   Wu X, Lu W, Streacker L M, Ashbaugh H S, Ben-Amotz D, Temperature-dependent hydrophobic crossover length scale and water tetrahedral order, J Phys 

        Chem Lett, 9(2018)1012-1017.

24.   Wu X, Lu W, Streacker L M, Ashbaugh H S, Ben-Amotz D, Methane hydration-shell structure and fragility, Angew Chem Int Ed, 57(2018)15133-15137.

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Asian Journal of Physics                                                                                                           Vol. 30 No 2, 2021, 347-352


Spectroscopic investigation about the influence of charge of cation on the
interaction of zwitterionic liposomes with minor groove of DNA


Tonima Nandy, and Prashant Chandra Singh*

School of Chemical Sciences

Indian Association for the Cultivation of Sciences, Jadavpur, Kolkata- 700 032, India

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

Fluorescence spectroscopy has been applied to study the influence of cations (Na+, Mg2+ and La3+) of various charges on the interaction of zwitterionic liposome with the minor groove of DNA. It has been found that DPPC does not interact with the minor groove of DNA in the presence of Na+. However, the interaction of DPPC is enhanced with the minor groove of DNA in the presence of Mg2+ and La3+ and the effect is more profound in the case of La3+. This study depicts that ionic charges can modulate the interaction of DPPC liposome with DNA minor groove which will be helpful in designing the drug delivery system. © Anita Publications. All rights reserved.

Keywords: Lipid, DNA, Minor Groove, Simulation, Charge.

References

  1.   Aveling E, Jun Z, Lim Y F, Mozafari M R, Targeting lipidic nanocarriers: current strategies and problems, Pharmakeftiki, 19(2006) 101-109.

  2.   Danaei M, Dehghankhold M, Ataei S, Davarani F H, Javanmard, R, Dokhani A, Khorasani S, Mozafari M R, Impact of Particle Size and Polydispersity Index 

        on the Clinical Applications of Lipidic Nanocarrier Systems, Pharmaceutics, 10(2018)57; doi. org/10.3390/pharmaceutics10020057.

  3.   Demetzos C, Application of Nanotechnology in Drug Delivery and Targeting, Pharmaceutical Nanotechnology, (Springer), 2016, 77-145.

  4.   Israelachvili J N, Marčelja S, Horn R G, Physical principles of membrane organization, Q Rev Biophys, 13 (2009) 121-200.

  5.   Langner M, Kubica K, The electrostatics of lipid surfaces, Chem Phys Lipids, 101(1999)3-35.

  6.   Knobloch J, Suhendro D K, Zieleniecki J L, Shapter J G, Köper I, Membrane-drug interactions studied using model membrane systems, Saudi J Biol Sci

        22(2015)714-718.

  7.   Clarke R J, Lüpfert C, Influence of Anions and Cations on the Dipole Potential of Phosphatidylcholine Vesicles: A Basis for the Hofmeister Effect, Biophys J

        76(1999)2614-2624.

  8.   Lo Nostro P, Ninham B W, Hofmeister Phenomena: An Update on Ion Specificity in Biology, Chem Rev, 112 (2012)2286-2322.

  9.   Kurland R, Newton C, Nir S, Papahadjopoulos D, Specificity of Na+ binding to phosphatidylserine vesicles from a 23Na NMR relaxation rate study. 

        Biochimica et biophysica acta, 551 (1979)137-47.

10.   Le C T M, Houri A, Balage N, Smith B J, Mechler A, Interaction of Small Ionic Species With Phospholipid Membranes: The Role of Metal Coordination. 

        Front Mater, 5 (2019)1-9.

11.   Omel'Chenko A M, Specific Adsorption of Metal Cations on the Surface of Lipid Membrane Systems, in Environmental Biotechnology, Blažej A, Prívarová V 

        (eds), (Elsevier), 1991.

12.   De S K, Kanwa N, Ahamed M, Chakraborty A, Spectroscopic evidence for hydration and dehydration of lipid bilayers upon interaction with metal ions: a new 

        physical insight, Phys Chem Chem Phys, 20(2018)14796-14807.

13.   Jurkiewicz P, Cwiklik L, Vojtíšková A, Jungwirth P, Hof M, Structure, dynamics, and hydration of POPC/POPS bilayers suspended in NaCl, KCl, and CsCl 

        solutions, Biochimica et biophysica acta, 1818(2012)609-616.

14.   Lis L J, Kauffman J W, Shriver D F, Effect of ions on phospholipid layer structure as indicated by Raman Spectroscopy. Biochimica et biophysica acta

        406(1975)453-464.

15.   Gruzdev A D, Khramtsov V V, Weiner L M, Budker V G, Fluorescence polarization study of the interaction of biopolymers with liposomes, FEBS Lett

        137(1982)227-230.

16.   Tarahovsky Y S, Khusainova R S, Gorelov A V, Nicolaeva T I, Deev A A, Dawson A K, Ivanitsky G R, DNA initiates polymorphic structural transitions in 

        lecithin, FEBS Lett, 390(1996)133-136.

17.   Wu C-M, Chen H.-L, Liou W, Lin T-L, Jeng U S, DNA-Induced Aggregation of Zwitterionic Oligolamellar Liposome. Biomacromolecules, 5(2004)2324-

        2328.

18.   Manzini G, Barcellona M L, Avitabile M, Quadrifoglio F, Interaction of diamidino-2-phenylindole (DAPI) with natural and synthetic nucleic acids, Nucleic 

        Acids Res, 11(1983)8861-8876.

19.   Zimmer C, Wähnert U, Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological 

        investigations of the genetic material, Prog Biophys Mol Biol, 47(1986)31-112.

20.   Banerjee D, Pal S K, Excited-State Solvation and Proton Transfer Dynamics of DAPI in Biomimetics and Genomic DNA, J Phys Chem A, 112(2008)7314-

        7320.

21.   Nandy T, Biswas B, Singh P C, Molecular aspects of the role of groove and stacked regions of DNA in binding with lipids: Spectroscopic and docking 

        studies, J Mol Liq, 303(2020)112672; doi.org/10.1016/j.molliq.2020.112672.

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Asian Journal of Physics                                                                                                       Vol. 30 No 2, 2021, 381-404


Comparison of molecular structure, Hirshfeld surface, vibrational spectra and nonlinear optical property of 

3-chloro- 4-fluroaniline and 2-iodoaniline with p-iodoaniline and p-bromoaniline 

on the basis of density functional theory


Nimmy L John and Sunila Abraham

Post Graduate & Research Department of Physics, Research Centre of University of Kerala, 

Christian College, Chengannur- 689 122 , India

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

Density functional theoretical computations were performed to obtain structural geometry, Hirshfeld surface, vibrational spectra and NLO property of 3-chloro-4-fluroaniline and 2-iodoaniline and results are compared with p-iodoaniline and p-bromoaniline. Hirshfeld surface analysis represented in the 2D fingerprint plot shows the presence of strong and weak intermolecular interactions within the dimer molecules. The HOMO-LUMO energy gap 4.6926 eV in 2-IA and 4.9377 eV in 3C4FA is an evidence for intra-molecular charge transfer interactions (π → π* as well as n → π*) within the molecules enhancing NLO activity. FT-IR, FT-Raman and UV-visible spectra of the compounds are simulated and compared with the corresponding experimental spectra. © Anita Publications. All rights reserved.

Keywords: FT-Raman, FT-IR, Hirshfeld surface, Hyper polarizability, Nonlinear optical activity

Reference

  1.  Yamamoto N, Ohashi K, Hino K, Izutsu H, Mogi K, Sakai Y, Sekiya H, Density functional studies on aniline dimer cations, Chem Phys Lett, 345(2001)532-

       538.

  2.  Wojciechowski P M, Michalska D, Theoretical Raman and infrared spectra, and vibrational assignment for para-halogenoanilines: DFT study, Spectrochim 

       Acta, A68(2007)948-955.

  3.  Sun X B, Wang X Q, Ren Q, Zhang G H, Yang H L, Feng L, Third-order nonlinear optical properties of bis (tetrabutylammonium) bis (4, 5-dithiolato-1, 3-

       dithiole-2-thione) copper, Mater Res Bull, 41(2006)177-182.

  4.  George M, John N L, Kumar M S, Sajan D, Physico-chemical studies of the experimental and theoretical properties of organic nonlinear optical material 4-

       chloro-4'methoxy benzylideneaniline, J Mol Struct, 1128(2016)754-768.

  5.   Kubota M, Ohba S, Electron-density distribution in fluorobenzene derivatives, Acta Cryst B, 48(1992)849-854.

  6.   Parkin A, Christopher K, Pulham R, 2-Iodoaniline at 100 K, Acta Crystallogr E, 61(2005)1087-1089.

  7.   Wojciechowski P, Helios K, Michalska D, Theoretical anharmonic Raman and infrared spectra with vibrational assignments for monofluoroaniline isomers, 

        Vib Spectrosc, 57(2011)126-134.

  8.   Gee C, Douin S, Crepin C, Brechignac P, Infrared spectroscopy of aniline (C6H5NH2) and its cation in a cryogenic argon matrix,, Chem Phys Lett

        338(2001)130-136.

  9.   Wojciechowski P M, Zierkiewicz W, Michalska D, Hobza P, Electronic structures , vibrational spectra , and revised assignment of aniline and its radical 

        cation : Theoretical study, J Chem Phys, 118(2003)10900-10911.

10.   John N L, Abraham S, Sajan D, Sarojini B K, Narayana B, Third order nonlinear optical properties, Structural, electronic and Vibrational Spectra of monomer 

        and dimer structures of para-iodoaniline and para-bromoaniline using density functional theory, J Mol Struct, 1222(2020)128939; doi. 

        org/10.1016/j.molstruc.2020.128939.

11.   Frisch G, Trucks H, Schlegel M, Gaussian 09. (Inc Wallingford),2009.

12.   Woon D E, Dunning T H, Gaussian basis sets for use in correlated molecular calculations. III. The atoms aluminum through argon, J Chem Phys

        98(1993)1358-1371.

13.   Glendening J, Badenhoop A, Reed J, Carpenter J, Bohmann C, Morales F, Weinhold E, NBO 5.0. (Theor Chem Institute, University of Wisconsin, Madison), 

        2001

14.   Mckinnon J J, Spackman M A, Mitchell A S, Novel tools for visualizing and exploring intermolecular interactions in molecular crystals, Struct Sci

        60(2004)627-668.

15.   Kvick A, Backeus M, Hydrogen Bond Studies. LXXXI.The Crystal and Molecular Structure of 2-Amino-5-chloropyridine, C5H3N(NH2)Cl, Acta Cryst B

        40(1974)474-480.

16.   Sundius T, Scaling of ab initio force fields by MOLVIB, Vib Spectrosc, 29(2002)89-95.

17.   Fuhrer V B, Kartha K L, Kidd P J, Kruger H H. Mantsch H, Computer Program for Infrared and Spectrometry, Normal Coordinate Analysis, Vol 5, (Ottawa, 

        National Research Council: Canada), 1976.

18.   Lister D G, Tyler J K, Høg J H, Larsen N W, The microwave spectrum, structure and dipole moment of aniline, J Mol Struct, 23(1974)253-264.

19.   Samdal S, Vilkov L, Volden H, The molecular structure of ortho-and meta-lodonitrobenzene in the gaseous state as determined by the electron diffraction 

        method, Acta Chem Scand, 46(1992)712-719.

20.   Hirshfeld F L. Bonded-Atom Fragments for Describing Molecular Charge Densities, Theor Chim Acta, 44(1977)129-138.

21.   Palafox M A, Rastogi R, Anupama, Alam M J, Daisy B, Rastogi V K, The accuracy of the M06L DFT method in the prediction of the vibrational Spectra of 4-

        amino-2-chlorobenzonitrile:A detailed interpretation of the Molecular Structure and vibrational IR and Raman spectra and other molecular properties using 

        several DFT methods, Asian J Phys, 25(2016)199-229.

22.   Dey A, Jetti R K R, Roland B, Desiraju G R, upramolecular equivalence of halogen , ethynyl and hydroxy groups. A comparison of the crystal structures of 

        some 4-substituted anilines, Cryst Eng Comm, 5(2003)248-252.

23.   Arivazhagan M, Subhasini V P, Austine A, Vibrational spectroscopic, first-order hyperpolarizability and HOMO, LUMO studies of 4-chloro-2-

        (trifluoromethyl) aniline based on DFT calculations, Spectrochim Acta, A86(2012)205-213.

24.   Socrates G, Infrared characteristic group frequencies. (Wiley-Interscience: England) 2000.

25.   Alcolea Palafox M, Rastogi V K, Guerrero-Martı´nez A, Tardajos G, Joe H, Vats J K, Simulation of a tetramer form of 5-iodouracil: The vibrational spectra 

        and molecular structure in the isolated and in the solid state by using DFT calculations, Vib Spectrosc, 52(2010)108-121.

26.   Thanikaivelan P, Subramanian V, Rao J R, Nair B U, Application of quantum chemical descriptor in quantitative structure activity and structure property 

        relationship, Chem Phys Lett, 323(2000)59-70.

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Asian Journal of Physics                                                                                                       Vol. 30 No 2, 2021, 405-411


Improved color properties of light emitting diodes with red phosphors and quantum dots


Jun Yeong Kim1, Hye-Rin Kim1, Yong Jin Lee1, In Sung Choi1, Jung-Gyun Lee1, Jae-Hyeon Ko1, Yongduk Kim2, Taehee Park3, and Young Wook Ko3

1School of Nano Convergence Technology, Hallym University, Chuncheon, Gangwondo 24252, Korea

2Cheorwon Plasma Research Institute, Cheorwon-gun, Gangwon-do, 24062, Korea

3GLVISION Co, Ltd., Geumgang-ro, Seo-myeon, Cheorwon-gun, Gangwon-do, 24062, Korea

This paper is dedicated to Prof Wolfgang Kiefer on the occasion of his 80th Birthday

___________________________________________________________________________________________________________________________________

This paper presents the effect of red color-conversion materials on the emitting spectrum of typical light emitting diodes (LEDs) for general lighting applications. Conventional LEDs consist of blue LED chips and yellow phosphors lacking deep red in their emitting spectra. Addition of red phosphors or red quantum dots may improve the color-rendering properties of white LEDs. Either the K2SiF6:Mn4+(KSF) red phosphor or red CdSe/ZnS quantum dot was included in the white LED made by using blue LEDs and YAG(Y3Al5O12:Ce3+) green phosphors. Inclusion of red emitting materials enhanced the color rendering index(CRI) significantly, especially the R9 index associated with the strong red. In addition, it was found that the improved white LEDs could be used to enhance the color gamut of liquid crystal displays. © Anita Publications. All rights reserved.

Keywords: Light emitting diode, Phosphor, Quantum dot, Color rendering index, Color gamut

References

  1.   Schubert E F, Kim J K, Luo H, Xi J-Q, Solid-state lighting—a benevolent technology, Rep Prog Phys, 69(2006)3069-3099.

  2.   Zhmakin A I, Enhancement of light extraction from light emitting diodes, Phys Rep, 498(2011)189-241.

  3.   Ko J-H, Recent research trends in the development of new light sources for the backlight unit of liquid crystal display, Asian J Phys, 14(2005)231-237.

  4.   Krames M R, Shchekin O B, Mueller-Mach R, Mueller G O, Zhou L, Harbers G, Craford M G, Status and Future of High-Power Light-Emitting Diodes for

        Solid-State Lighting, J Disp Tech, 3(2007)160-175.

  5.   Lin C C, Meijerink A, Liu R-S, Critical Red Components for Next-Generation White LEDs, J Phys Chem Lett, 7(2016)495-503.

  6.   Wu W-L, Fang M-H, Zhou W, Lesniewski T, Mahlik S, Grinberg M, Brik M G, Sheu H-S, Cheng B-M, Wang J, Liu R-S, High Color Rendering Index of

        Rb2GeF6:Mn4+ for Light-Emitting Diodes, Chem Mater, 29(2017)935-939.

  7.   Luo D, Wang L, Or S W, Zhang H, Xie R-J, Realizing superior white LEDs with both high R9 and luminous efficacy by using dual red phosphors, RSC Adv,

        7(2017)25964-25968.

  8.   Kim M, Park W B, Bang B, Kim C H, Sohn K-S, Radiative and non-radiative decay rate of K2SiF6:Mn4+ phosphors, J Mater Chem C, 3(2015)5484-5489.

  9.   Jeong D Y, Ju J, Kim D H, Optimized Photoluminescence of K2SiF6:Mn4+ Phosphors for LED Solid-state Lighting, New Phys: Sae Mulli, 66(2016)311-316.

10.   Nizamoglu S, Erdem T, Sun X W, Demir H V, Warm-white light-emitting diodes integrated with colloidal quantum dots for high luminous efficacy and color

        rendering, Opt Lett, 35(2010)3372-3374.

11.   Denault K A, Mikhailovsky A A, Brinkley S, Baars S P D, Seshadri R, Improving color rendition in solid state white lighting through the use of quantum dots,

        J Mater Chem C, 1(2013)1461-1466.

12.   Jo D -Y, Yang H, Spectral broadening of Cu–In–Zn–S quantum dot color converters for high color rendering white lighting device, J Lumin,

        166(2015)227-232.

13.   Chung S-R, Chen S-S, Wang K-W, Siao C-B, Promotion of solid-state lighting for ZnCdSe quantum dot modified-YAG-based white light emitting diodes,

        RSC Adv, 6(2016)51989-51996.

14.   Yoon H C, Oh J H, Lee S, Park J B, Do Y R, Circadian-tunable Perovskite Quantum Dot-based Down-Converted Multi-Package White LED with a Color

        Fidelity Index over 90, Sci Rep, 7(2017)2808; doi.org/10.1038/s41598-017-03063-7.

15.   Shirasaki Y, Supran G J, Bawendi M G, Bulović V, Emergence of colloidal quantum-dot light-emitting technologies, Nat Photon, 7(2013)13-23.

16.   Kim S J, Jang H W, Lee J-G, Ko J-H, Ko Y W, Kim Y, Study on Improvements in the Emission Properties of Quantum-Dot Film-Based Backlights, New Phys:

        Sae Mulli, 69(2019)861-866.

17.   S C Hong, J Baek, H Lee, G J Lee, J -G Lee, J -H Ko, Y W Ko, Y Kim, T Park, Study on the Improvement of the Color Rendering Index of White LEDs by

        Using red Quantum dots, New Phys: Sae Mulli, 70(2020)698-704.

Improved color properties of light emitting diodes with red phosphors and quantum dots.pdf
Jae-Hyeon Ko and et al

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Asian Journal of Physics                                                                                                                            Vol. 30 No 2, 2021, i-iii

Book Review
C V Raman and the Press: Scientific Reporting and Image Building  

(Part III: The Raman Research Institute Period)
Author: Dr. Rajinder Singh, University of Oldenburg, Germany.
Publishers: Shaker Publisher, Dueren, Germany,
Year of Publication 2020,
Pages XIV + 119 .
Price, Digital: 5,47 Euro, Paperback: 21,90 Euro.
ISBN: -- 978-3-8440-7520-5.
    The present book is the third and the last part of the trilogy entitled “C V Raman and the Press: Science Reporting and Image Building.” It chronicled Raman’s last phase of service career at the Raman Research Institute (RRI), Bangalore during 1948-1970. The first and the second parts of  the sequel profiled his life in Calcutta (1917-1933) and Bangalore(1933-1948).
book_review_C V Raman and the Press: Scientific Reporting and Image Building.pdf
Dr Anjana Chattopadhyay

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